Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis
Published: July 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/48795.15099
Sowrabha Bhat, Subhodip Pramanik, Pradip Mukhopadhyay, Subhankar Chowdhury
1. Consultant Endocrinologist, Department of Endocrinology, Chinmaya Mission Hospital, Bengaluru, Karnataka, India
2. Consultant Endocrinologist, Department of Endocrinology, Neotia Getwel Healthcare Siliguri, West Bengal, India.
3. Professor, Department of Endocrinology, IPGMER, Kolkata, West Bengal, India.
4. Professor and Head, Department of Endocrinology, IPGMER, Kolkata, West Bengal, India.
Correspondence
Dr. Subhodip Pramanik,
Flat No. 601, Tower 1, HIG Apartment, Siliguri, West Bengal, India.
E-mail: subhodip.mck@gmail.com
Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes. Diabetic Ketoacidosis (DKA) is a rare but known complication of diabetes in acromegaly. Most cases of acromegaly come into light due to the classical soft tissue changes in the face and extremities. A high index of suspicion is required to diagnose this condition in early stage. Here, a case of 22-years-old male presented with DKA and on investigation was found to have acromegaly due to a GH secreting pituitary macroadenoma. This management and subsequent follow-up of the case along with review of literature is also done. Such a presentation of acromegaly was rare but rewarding.
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